Pharmacogenomics (PGx) Drug List

Actionable medications with established pharmacogenetic associations

Oncology / Cancer Therapeutics

Drug
atazanavir
capecitabine
fluorouracil
irinotecan
mercaptopurine
tamoxifen
thioguanine

Mental Health & Central Nervous System

Drug
amitriptyline
amoxapine
aripiprazole
aripiprazole lauroxil
aripiprazole lauroxil (submicronized)
atomoxetine
brexpiprazole
carbamazepine
citalopram
clomipramine
desipramine
desvenlafaxine
deutetrabenazine
diazepam
doxepin
duloxetine
escitalopram
fluoxetine
fluvoxamine
fosphenytoin
haloperidol
iloperidone
imipramine
levomilnacipran
milnacipran
nortriptyline
oxcarbazepine
paroxetine
perphenazine
phenytoin
pimozide
protriptyline
risperidone
sertraline
siponimod
thioridazine
trimipramine
venlafaxine
vilazodone
viloxazine
vortioxetine
xanomeline/trospium

Supportive Care: Pain, Fever, & Anesthesia

Drug
aceclofenac
aspirin
celecoxib
codeine
diclofenac
hydrocodone
ibuprofen
indomethacin
ketorolac
lornoxicam
lumiracoxib
meloxicam
metamizole
nabumetone
naproxen
piroxicam
sulindac
tenoxicam
tramadol

Supportive Care: Gastrointestinal & Digestive

Drug
dexlansoprazole
esomeprazole
lansoprazole
metoclopramide
omeprazole
ondansetron
pantoprazole
rabeprazole
rasburicase
tropisetron

Cardiovascular / Hematology

Drug
acebutolol
apixaban
atenolol
betaxolol
bisoprolol
carvedilol
clopidogrel
dabigatran
esmolol
fluvastatin
labetalol
mavacamten
metoprolol
nadolol
nebivolol
pindolol
prasugrel
propranolol
rivaroxaban
sotalol
ticagrelor
warfarin

Rheumatology, Immunology, & Infectious Disease

Drug
abacavir
allopurinol
azathioprine
colchicine
dapsone
febuxostat
flucytosine
nitrofurantoin
posaconazole
primaquine
probenecid
sulfasalazine
tafenoquine
voriconazole

Urinary & Other Specialty Categories

Drug
flurbiprofen
pegloticase
tamsulosin
methylene blue
toluidine blue

Disclaimer: This list is for educational and reference purposes. Always consult current FDA labels, CPIC guidelines, or a clinical pharmacist for patient-specific recommendations. Silver Gene Labs © 2026